Foldamer-based ultrapermeable and highly selective artificial water channels that exclude protons
نویسندگان
چکیده
منابع مشابه
Ultrapermeable, reverse-selective nanocomposite membranes.
Polymer nanocomposites continue to receive tremendous attention for application in areas such as microelectronics, organic batteries, optics, and catalysis. We have discovered that physical dispersion of nonporous, nanoscale, fumed silica particles in glassy amorphous poly(4-methyl-2-pentyne) simultaneously and surprisingly enhances both membrane permeability and selectivity for large organic m...
متن کاملHighly permeable artificial water channels that can self-assemble into two-dimensional arrays.
Bioinspired artificial water channels aim to combine the high permeability and selectivity of biological aquaporin (AQP) water channels with chemical stability. Here, we carefully characterized a class of artificial water channels, peptide-appended pillar[5]arenes (PAPs). The average single-channel osmotic water permeability for PAPs is 1.0(± 0.3) × 10(-14) cm(3)/s or 3.5(± 1.0) × 10(8) water m...
متن کاملWhy can't protons move through water channels?
Aquaporins are proteins with a hole down their middle that allow the flow of water (Agre and Kozono, 2003) through otherwise impermeable membranes and thus make the life of (animal) cells possible, as we know it (Agre et al., 1998). The membranes of animal cells are weak, not able to maintain significant pressures, and so water must flow easily out of cells if they are to survive with membranes...
متن کاملRecombinant pICln Forms Highly Cation-selective Channels when Reconstituted into Artificial and Biological Membranes
pICln has been proposed to be the swelling-activated anion channel responsible for ICl, swell, or a channel regulator. We tested the anion channel hypothesis by reconstituting recombinant pICln into artificial and biological membranes. Single channels were observed when pICln was reconstituted into planar lipid bilayers. In the presence of symmetrical 300 mM KCl, the channels had a high open pr...
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ژورنال
عنوان ژورنال: Nature Nanotechnology
سال: 2021
ISSN: 1748-3387,1748-3395
DOI: 10.1038/s41565-021-00915-2